🇷🇴Europe

Medical Device Regulation in Romania

Romania regulates medical devices under the EU Medical Device Regulation (EU MDR 2017/745) as an EU member state. The National Agency for Medicines and Medical Devices (ANMDMR) is the national competent authority. Romania has a growing medical device market and aligns its regulatory framework fully with EU requirements.

FrameworkEU Medical Device Regulation (EU MDR 2017/745); EU In Vitro Diagnostic Regulation (EU IVDR 2017/746); Romanian Government Emergency Ordinance No. 46/2021 adapting national legislation to EU MDR.
Classification systemClass I / Class IIa / Class IIb / Class III
Primary agencyANMDMR
RegionEurope
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Updates this year0

Sources Tracked by Qalico

Qalico continuously monitors 0 references across guidelines, regulations, and standards for Romania.

Device Classification

Class IClass IIaClass IIbClass III

Romania follows the EU MDR Annex VIII classification system. Class I includes low-risk devices such as bandages and manual surgical instruments. Class IIa includes medium-risk devices like surgical sutures and ultrasound diagnostic devices. Class IIb includes higher-risk devices such as infant incubators and X-ray equipment. Class III includes the highest-risk devices such as prosthetic heart valves and spinal disc replacements.

Official classification guidance →

Standards & Key Principles

Applicable Standards

ISO 13485 – Quality Management Systems for Medical DevicesISO 14971 – Risk Management for Medical DevicesIEC 60601 – Safety and Performance of Medical Electrical EquipmentIEC 62304 – Medical Device Software Lifecycle ProcessesISO 10993 – Biological Evaluation of Medical Devices

Key Principles

  • CE marking is mandatory for all medical devices placed on the Romanian market under EU MDR 2017/745.
  • Economic operators must register with ANMDMR before placing devices on the market.
  • Romanian language labeling and instructions for use are required for devices used by lay persons.
  • Clinical investigations conducted in Romania require ANMDMR authorization and ethics committee approval.
  • UDI requirements follow EU MDR timelines.

Pre-Market Requirements

Conformity Assessment

Manufacturers must undergo conformity assessment per EU MDR requirements. Notified Body involvement is required for Class IIa, IIb, and III devices.

CE Marking

All medical devices must bear the CE mark before being placed on the Romanian market.

National Registration

Manufacturers and economic operators must notify ANMDMR of devices placed on the Romanian market.

Technical Documentation

Comprehensive technical documentation per EU MDR Annexes II and III must be prepared, including clinical evaluation and risk management data.

Post-Market Requirements

Post-Market Surveillance (PMS)

Manufacturers must maintain PMS systems in compliance with EU MDR Chapter VII to monitor device safety and performance.

Vigilance Reporting

Serious incidents and field safety corrective actions must be reported to ANMDMR in accordance with EU MDR requirements.

Periodic Safety Update Reports (PSUR)

PSURs are required for Class IIa, IIb, and III devices, with summaries of benefit-risk assessments and PMS findings.

International Recognition & Reliance

European Union

As an EU member state, Romania recognizes CE-marked devices certified by any EU-designated Notified Body under the EU MDR.

Stay on top of regulatory changes in Romania

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